Our lab uses an interdisciplinary approach to study the role of glial cells in neural development and disease.
Glia play diverse roles in the CNS are associated with numerous neurological disorders and malignancies. In spite of their vital role in CNS physiology and pathology, the molecular mechanisms that control their development and diversity remain poorly defined; accordingly, how these processes contribute to CNS pathology also remains undefined.
GLIAL BIOLOGY
Our studies focus on the identification of novel molecular signaling and regulatory pathways in glial development using chick and mouse model systems, biochemical techniques, and an array of complex CNS injury models.
These studies will provide the foundations to translate developmentally relevant findings to demyelinating diseases and neurodegenerative disorders in an effort to develop therapeutic interventions.
